Medications used for covid-19 treatment and a comparison of their mechanism of action and therapeutic efficacy

Abstract

Coronavirus disease 2019 also known as COVID-19, is an acute respiratory condition (Severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2) caused by a novel coronavirus that was discovered for the first time in Wuhan, China’s Hubei Province, during a respiratory illness outbreak. The World Health Organization declared the COVID-19 pandemic a worldwide health emergency. The aim of this article is to evaluate the drugs that are currently used for the COVID 19 treatment and to outline the mechanism of actions and therapeutic efficacy of these drugs along with the comparison between them. This review has been conducted with a comprehensive literature analysis of clinical characteristics and therapies of the novel COVID 19 using internet databases with the recent relevant publications and research. Remdesivir, dexamethasone and amantadine are more effective than other drugs for people who are hospitalized with COVID-19 and need supplemental oxygen or have a higher risk of serious illness.