Investigation of In-vitro antioxidant potential, brine shrimp lethality and Thrombolytic activity in Ficus mollis vahl Leaves along with phytochemical screening

Abstract

In the present study, the methanolic extract of Ficus molis vahl from Moraceae family was investigated for various phytochemical and biological properties, Chemical test were performed to check the presence of phytochemicals. The leaf extract proved positive result for the existence of alkaloids, carbohydrates, flavonoids, phytosterols, glycosides, resins, saponins, tannins e.t.c. However, the test results confirmed the absence of Phenols/Phenolic compounds, Glycosides, Resins, Steroids, Saponin and Phlobatannins. In order to investigate the biological property such as antioxidant activity, the DPPH free radical scavenging activity and total phenolic content was determined. In vitro cytotoxic potential of methanolic extract of Ficus Molis vahl was also performed utilizing the brine shrimp lethality assay. Ficus Molis vahl leaf extract showed antioxidant property, cytotoxicity property and thrombolytic property, as end result showed that the plant extract possess moderate antioxidant activity and cytotoxic potential at higher concentrations.