Antioxidant and hypoglycemic effect of Nypa Fruticans wurmb fruit shell

Abstract

Plant extract-based natural medicines are becoming more and more popular as a substitute for synthetic drugs, which raises safety concerns. This study examined Nypa fruticans's hypoglycemic and antioxidant impact. We have chosen to assess the antioxidant and hypoglycemic qualities of the methanolic extract of N. frutican’s fruit shell (MNF) to demonstrate this. So, DPPH (1, 1 diphenyl-2-picryl hydrazyl) test was done for the percentage scavenging of methanolic extract of N.fruticans in contrast to Ascorbic acid for antioxidant activities This study shows that the N.fruticans fruit shell sample's methanolic extract has an IC50 value of 50.59 g/ml, which is indicative of its antioxidant properties, compared to the potent antioxidant ascorbic acid's IC50 value of 44.11 g/ml. Swiss albino mice were given 10% glucose solution as a reference medication and allowed to undergo the Oral glucose tolerance test (OGTT) for one to three hours. Following an hour, the NFS600 glucose level declined to 12.17±2.36, which is almost identical to the usual 8.58±1.84. The remaining outcomes followed one another. Because of this, the methanolic shell of N. fruticans has antioxidant and hypoglycemic properties that may help advance medical research in the area of diabetes diagnosis.